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Reduction of Histone Marks, H3K9me3 and H3K27me3 by Epidrug Induces Neuroendocrine Differentiation in Prostate Cancer
Neuroendocrine prostate cancer (NE PCa) is an aggressive malignancy, often presenting with advanced metastasis. We previously reported that reduction of histone marks regulated by DNMT1 following epidrug (5-Azacitidine, 5-Aza) treatment controls induction of epithelial to mesenchymal (EMT) and a can...
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| Publicado no: | J Cell Biochem |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5826874/ https://ncbi.nlm.nih.gov/pubmed/29236331 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.26586 |
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