CTCF induces histone variant incorporation, erases the H3K27me3 histone mark and opens chromatin

Insulators functionally separate active chromatin domains from inactive ones. The insulator factor, CTCF, has been found to bind to boundaries and to mediate insulator function. CTCF binding sites are depleted for the histone modification H3K27me3 and are enriched for the histone variant H3.3. In or...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nucleic Acids Res
Egile Nagusiak: Weth, Oliver, Paprotka, Christine, Günther, Katharina, Schulte, Astrid, Baierl, Manuel, Leers, Joerg, Galjart, Niels, Renkawitz, Rainer
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2014
Gaiak:
Gene regulation, Chromatin and Epigenetics
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4231773/
https://ncbi.nlm.nih.gov/pubmed/25294833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku937
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