CTCF induces histone variant incorporation, erases the H3K27me3 histone mark and opens chromatin

Insulators functionally separate active chromatin domains from inactive ones. The insulator factor, CTCF, has been found to bind to boundaries and to mediate insulator function. CTCF binding sites are depleted for the histone modification H3K27me3 and are enriched for the histone variant H3.3. In or...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Nucleic Acids Res
Päätekijät: Weth, Oliver, Paprotka, Christine, Günther, Katharina, Schulte, Astrid, Baierl, Manuel, Leers, Joerg, Galjart, Niels, Renkawitz, Rainer
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2014
Aiheet:
Gene regulation, Chromatin and Epigenetics
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4231773/
https://ncbi.nlm.nih.gov/pubmed/25294833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku937
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