CTCF induces histone variant incorporation, erases the H3K27me3 histone mark and opens chromatin

Insulators functionally separate active chromatin domains from inactive ones. The insulator factor, CTCF, has been found to bind to boundaries and to mediate insulator function. CTCF binding sites are depleted for the histone modification H3K27me3 and are enriched for the histone variant H3.3. In or...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Weth, Oliver, Paprotka, Christine, Günther, Katharina, Schulte, Astrid, Baierl, Manuel, Leers, Joerg, Galjart, Niels, Renkawitz, Rainer
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Gene regulation, Chromatin and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4231773/
https://ncbi.nlm.nih.gov/pubmed/25294833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku937
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