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Novel kinetic intermediates populated along the folding pathway of the transmembrane β-barrel OmpA

We examined the folding of the β-barrel membrane protein OmpA from E. coli. Although previous studies identified several intermediate states followed by a concerted translocation mechanism across the bilayer, some aspects of the pathway were still unclear including the extent of secondary structure...

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Publicado en:Biochemistry
Autores principales: Danoff, Emily J., Fleming, Karen G.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5826654/
https://ncbi.nlm.nih.gov/pubmed/28001375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b00809
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