Histone Deacetylase 3 Prepares Brown Adipose Tissue For Acute Thermogenic Challenge

Brown adipose tissue (BAT) is a thermogenic organ that dissipates chemical energy as heat to protect animals against hypothermia and to counteract metabolic disease(1). However, the transcriptional mechanisms that determine BAT thermogenic capacity prior to environmental cold are unknown. Here we sh...

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Published in:Nature
Main Authors: Emmett, Matthew J., Lim, Hee-Woong, Jager, Jennifer, Richter, Hannah J., Adlanmerini, Marine, Peed, Lindsey C., Briggs, Erika R., Steger, David J., Ma, Tao, Sims, Carrie A., Baur, Joseph A., Pei, Liming, Won, Kyoung-Jae, Seale, Patrick, Gerhart-Hines, Zachary, Lazar, Mitchell A.
Format: Artigo
Language:Inglês
Published: 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5826652/
https://ncbi.nlm.nih.gov/pubmed/28614293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature22819
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