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SGK1 Governs the Reciprocal Development of Th17 and Regulatory T Cells

A balance between Th17 and regulatory T (Treg) cells is critical for immune homeostasis and tolerance. Our previous work has shown Serum- and glucocorticoid-induced kinase 1 (SGK1) is critical for the development and function of Th17 cells. Here, we show that SGK1 restrains the function of Treg cell...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Wu, Chuan, Chen, Zuojia, Xiao, Sheng, Thalhamer, Theresa, Madi, Asaf, Han, Timothy, Kuchroo, Vijay
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5826610/
https://ncbi.nlm.nih.gov/pubmed/29346764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.12.068
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