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Triclosan Enhances the Clearing of Pathogenic Intracellular Salmonella or Candida albicans but Disturbs the Intestinal Microbiota through mTOR-Independent Autophagy

Triclosan (TCS) is a broad-spectrum antimicrobial agent, whose well-known antibacterial mechanism is inhibiting lipid synthesis. Autophagy, an innate immune response, is an intracellular process that delivers the cargo including pathogens to lysosomes for degradation. In this study, we first demonst...

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Detalhes bibliográficos
Publicado no:Front Cell Infect Microbiol
Main Authors: Wang, Chao, Yu, Zhongyang, Shi, Xiaochen, Tang, Xudong, Wang, Yang, Wang, Xueyan, An, Yanan, Li, Shulin, Li, Yan, Wang, Xuefei, Luan, Wenjing, Chen, Zhaobin, Liu, Mingyuan, Yu, Lu
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5826388/
https://ncbi.nlm.nih.gov/pubmed/29515975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2018.00049
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