Triclosan Enhances the Clearing of Pathogenic Intracellular Salmonella or Candida albicans but Disturbs the Intestinal Microbiota through mTOR-Independent Autophagy

Triclosan (TCS) is a broad-spectrum antimicrobial agent, whose well-known antibacterial mechanism is inhibiting lipid synthesis. Autophagy, an innate immune response, is an intracellular process that delivers the cargo including pathogens to lysosomes for degradation. In this study, we first demonst...

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Vydáno v:Front Cell Infect Microbiol
Hlavní autoři: Wang, Chao, Yu, Zhongyang, Shi, Xiaochen, Tang, Xudong, Wang, Yang, Wang, Xueyan, An, Yanan, Li, Shulin, Li, Yan, Wang, Xuefei, Luan, Wenjing, Chen, Zhaobin, Liu, Mingyuan, Yu, Lu
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
Microbiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5826388/
https://ncbi.nlm.nih.gov/pubmed/29515975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2018.00049
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