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NRF2 regulates core and stabilizing circadian clock loops, coupling redox and timekeeping in Mus musculus
Diurnal oscillation of intracellular redox potential is known to couple metabolism with the circadian clock, yet the responsible mechanisms are not well understood. We show here that chemical activation of NRF2 modifies circadian gene expression and rhythmicity, with phenotypes similar to genetic NR...
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| Publicat a: | eLife |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
eLife Sciences Publications, Ltd
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5826263/ https://ncbi.nlm.nih.gov/pubmed/29481323 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.31656 |
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