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Suppression of Reactive Oxygen Species Accumulation Accounts for Paradoxical Bacterial Survival at High Quinolone Concentration

When bacterial cells are exposed to increasing concentrations of quinolone-class antibacterials, survival drops, reaches a minimum, and then recovers, sometimes to 100%. Despite decades of study, events underlying this paradoxical high-concentration survival remain obscure. Since reactive oxygen spe...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Luan, Gan, Hong, Yuzhi, Drlica, Karl, Zhao, Xilin
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5826153/
https://ncbi.nlm.nih.gov/pubmed/29229642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01622-17
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