Regulatory T-Cells Mediate IFN-α-Induced Resistance against Antigen-Induced Arthritis

OBJECTIVE: CD4(+)FoxP3(+)CD25(+) regulatory T-cells (T(regs)) are important for preventing tissue destruction. Here, we investigate the role of T(regs) for protection against experimental arthritis by IFN-α. METHODS: Arthritis was triggered by intra-articular injection of methylated bovine serum alb...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Chenna Narendra, Sudeep, Chalise, Jaya Prakash, Biggs, Sophie, Kalinke, Ulrich, Magnusson, Mattias
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5826073/
https://ncbi.nlm.nih.gov/pubmed/29515584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00285
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