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Replication Rapidly Recovers and Continues in the Presence of Hydroxyurea in Escherichia coli
In both prokaryotes and eukaryotes, hydroxyurea is suggested to inhibit DNA replication by inactivating ribonucleotide reductase and depleting deoxyribonucleoside triphosphate pools. In this study, we show that the inhibition of replication in Escherichia coli is transient even at concentrations of...
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| Publicado no: | J Bacteriol |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5826035/ https://ncbi.nlm.nih.gov/pubmed/29263100 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00713-17 |
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