A personalized, multiomics approach identifies genes involved in cardiac hypertrophy and heart failure

A traditional approach to investigate the genetic basis of complex diseases is to identify genes with a global change in expression between diseased and healthy individuals. However, population heterogeneity may undermine the effort to uncover genes with significant but individual contribution to th...

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Pubblicato in:NPJ Syst Biol Appl
Autori principali: Santolini, Marc, Romay, Milagros C., Yukhtman, Clara L., Rau, Christoph D., Ren, Shuxun, Saucerman, Jeffrey J., Wang, Jessica J., Weiss, James N., Wang, Yibin, Lusis, Aldons J., Karma, Alain
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5825397/
https://ncbi.nlm.nih.gov/pubmed/29507758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41540-018-0046-3
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