The soluble guanylate cyclase stimulator IW‐1973 prevents inflammation and fibrosis in experimental non‐alcoholic steatohepatitis

BACKGROUND AND PURPOSE: Non‐alcoholic steatohepatitis (NASH) is the hepatic manifestation of metabolic syndrome and is characterized by steatosis, inflammation and fibrosis. Soluble guanylate cyclase (sGC) stimulation reduces inflammation and fibrosis in experimental models of lung, kidney and heart...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Br J Pharmacol
Prif Awduron: Flores‐Costa, Roger, Alcaraz‐Quiles, José, Titos, Esther, López‐Vicario, Cristina, Casulleras, Mireia, Duran‐Güell, Marta, Rius, Bibiana, Diaz, Alba, Hall, Katherine, Shea, Courtney, Sarno, Renee, Currie, Mark, Masferrer, Jaime L, Clària, Joan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2018
Pynciau:
Research Papers
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5825296/
https://ncbi.nlm.nih.gov/pubmed/29281143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14137
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