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Molecular Insights into Cortico-striatal Miscommunications in Huntington’s Disease
Huntington’s disease (HD), a dominantly inherited neurodegenerative disease, is defined by its genetic cause, a CAG-repeat expansion in the HTT gene, its motor and psychiatric symptomology and primary loss of striatal medium spiny neurons (MSNs). However, the molecular mechanisms from genetic lesion...
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| Pubblicato in: | Curr Opin Neurobiol |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5825262/ https://ncbi.nlm.nih.gov/pubmed/29125980 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.conb.2017.10.019 |
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