MicroRNA-19a and microRNA-19b promote the malignancy of clear cell renal cell carcinoma through targeting the tumor suppressor RhoB

Clear cell renal cell carcinoma (ccRCC) is the most common subtype of renal cell carcinoma, which shows high aggressiveness and lacks biomarkers. RhoB acts as a tumor suppressor that inhibits the progression of ccRCC. In the present study, we examined the effects of oncogenic microRNAs, miR-19a and...

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Publicat a:PLoS One
Autors principals: Niu, Shaoxi, Ma, Xin, Zhang, Yu, Liu, Yen-Nien, Chen, Xufeng, Gong, Huijie, Yao, Yuanxin, Liu, Kan, Zhang, Xu
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5825063/
https://ncbi.nlm.nih.gov/pubmed/29474434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0192790
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