β-glucuronidase use as a single internal control gene may confound analysis in FMR1 mRNA toxicity studies

Relationships between Fragile X Mental Retardation 1 (FMR1) mRNA levels in blood and intragenic FMR1 CGG triplet expansions support the pathogenic role of RNA gain of function toxicity in premutation (PM: 55–199 CGGs) related disorders. Real-time PCR (RT-PCR) studies reporting these findings normali...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Kraan, Claudine M., Cornish, Kim M., Bui, Quang M., Li, Xin, Slater, Howard R., Godler, David E.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2018
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5825026/
https://ncbi.nlm.nih.gov/pubmed/29474364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0192151
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