Evidence for the toxicity of bidirectional transcripts and mitochondrial dysfunction in blood associated with small CGG expansions in the FMR1 gene in patients with parkinsonism

PURPOSE: Our previous results showed that both gray zone and lower end premutation range (40–85 repeats) fragile X mental retardation 1 (FMR1) alleles were more common among males with parkinsonism than in the general population. This study aimed to determine whether these alleles have a significant...

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Main Authors: Loesch, Danuta Z., Godler, David E., Evans, Andrew, Bui, Quang M., Gehling, Freya, Kotschet, Katya E., Trost, Nicholas, Storey, Elsdon, Stimpson, Paige, Kinsella, Glynda, Francis, David, Thorburn, David R., Venn, Alison, Slater, Howard R., Horne, Malcolm
格式: Artigo
語言:Inglês
出版: 2011
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022481/
https://ncbi.nlm.nih.gov/pubmed/21270637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/GIM.0b013e3182064362
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