Functionally distinct disease-associated fibroblast subsets in rheumatoid arthritis

Fibroblasts regulate tissue homeostasis, coordinate inflammatory responses, and mediate tissue damage. In rheumatoid arthritis (RA), synovial fibroblasts maintain chronic inflammation which leads to joint destruction. Little is known about fibroblast heterogeneity or if aberrations in fibroblast sub...

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Udgivet i:Nat Commun
Main Authors: Mizoguchi, Fumitaka, Slowikowski, Kamil, Wei, Kevin, Marshall, Jennifer L., Rao, Deepak A., Chang, Sook Kyung, Nguyen, Hung N., Noss, Erika H., Turner, Jason D., Earp, Brandon E., Blazar, Philip E., Wright, John, Simmons, Barry P., Donlin, Laura T., Kalliolias, George D., Goodman, Susan M., Bykerk, Vivian P., Ivashkiv, Lionel B., Lederer, James A., Hacohen, Nir, Nigrovic, Peter A., Filer, Andrew, Buckley, Christopher D., Raychaudhuri, Soumya, Brenner, Michael B.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5824882/
https://ncbi.nlm.nih.gov/pubmed/29476097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-02892-y
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