Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction

BACKGROUND. The link between mucus plugs and airflow obstruction has not been established in chronic severe asthma, and the role of eosinophils and their products in mucus plug formation is unknown. METHODS. In clinical studies, we developed and applied a bronchopulmonary segment–based scoring syste...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Dunican, Eleanor M., Elicker, Brett M., Gierada, David S., Nagle, Scott K., Schiebler, Mark L., Newell, John D., Raymond, Wilfred W., Lachowicz-Scroggins, Marrah E., Di Maio, Selena, Hoffman, Eric A., Castro, Mario, Fain, Sean B., Jarjour, Nizar N., Israel, Elliot, Levy, Bruce D., Erzurum, Serpil C., Wenzel, Sally E., Meyers, Deborah A., Bleecker, Eugene R., Phillips, Brenda R., Mauger, David T., Gordon, Erin D., Woodruff, Prescott G., Peters, Michael C., Fahy, John V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
Assuntos:
Clinical Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5824874/
https://ncbi.nlm.nih.gov/pubmed/29400693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI95693
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