A recurrent kinase domain mutation in PRKCA defines chordoid glioma of the third ventricle

Chordoid glioma is a rare brain tumor thought to arise from specialized glial cells of the lamina terminalis along the anterior wall of the third ventricle. Despite being histologically low-grade, chordoid gliomas are often associated with poor outcome, as their stereotypic location in the third ven...

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Publicado en:Nat Commun
Main Authors: Goode, Benjamin, Mondal, Gourish, Hyun, Michael, Ruiz, Diego Garrido, Lin, Yu-Hsiu, Van Ziffle, Jessica, Joseph, Nancy M., Onodera, Courtney, Talevich, Eric, Grenert, James P., Hewedi, Iman H., Snuderl, Matija, Brat, Daniel J., Kleinschmidt-DeMasters, Bette K., Rodriguez, Fausto J., Louis, David N., Yong, William H., Lopes, M. Beatriz, Rosenblum, Marc K., Butowski, Nicholas, Tihan, Tarik, Bollen, Andrew W., Phillips, Joanna J., Wiita, Arun P., Yeh, Iwei, Jacobson, Matthew P., Bastian, Boris C., Perry, Arie, Solomon, David A.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5824822/
https://ncbi.nlm.nih.gov/pubmed/29476136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-02826-8
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