GENE-54. A NOVEL MUTATION IN PRKCA IS THE MAJOR DRIVER OF CHORDOID GLIOMAS

BACKGROUND: Chordoid glioma (ChG) is a characteristic, slow growing and well-circumscribed diencephalic tumor, whose mutational landscape is unknown. METHODS: We analyzed primary chordoid glioma samples by whole exome sequencing, RNAseq, Sanger sequencing, RT-PCR and immunohistochemistry. We determi...

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Publicado en:Neuro Oncol
Autores principales: Rosenberg, Shai, Simeonova, Iva, Bielle, Franck, Verreault, Maite, Roux, Isabelle Le, Daniau, Mailys, Nadaradjane, Arun, Gleize, Vincent, Paris, Sophie, Marie, Yannick, Giry, Marine, Polivka, Marc, Branger, Dominique Figarella, Aubriot-Lorton, Marie-Hélène, Villa, Chiara, Vasiljevic, Alexandre, Lechapt-Zalcman, Emmanuèle, Kalamarides, Michel, Mokhtari, Karima, Pagnotta, Stefano, Iavarone, Antonio, Lasorella, Anna, Huillard, Emmanuelle, Sanson, Marc
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692411/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.426
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