Loss of eIF4E Phosphorylation Engenders Depression-like Behaviors via Selective mRNA Translation

The MAPK/ERK (mitogen-activated protein kinases/extracellular signal-regulated kinase) pathway is a cardinal regulator of synaptic plasticity, learning, and memory in the hippocampus. One of major endpoints of this signaling cascade is the 5′ mRNA cap binding protein eIF4E (eukaryotic Initiation Fac...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Amorim, Inês S., Kedia, Sonal, Kouloulia, Stella, Simbriger, Konstanze, Gantois, Ilse, Jafarnejad, Seyed Mehdi, Li, Yupeng, Kampaite, Agniete, Pooters, Tine, Romanò, Nicola, Gkogkas, Christos G.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5824745/
https://ncbi.nlm.nih.gov/pubmed/29367404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2673-17.2018
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