Eradication of triple negative breast cancer cells by targeting glycosylated PD-L1

Protein glycosylation provides proteomic diversity in regulating protein localization, stability and activity; it remains largely unknown whether the sugar moiety contributes to immunosuppression. In the study of immune receptor glycosylation, we showed EGF induces PD-L1 and receptor programmed cell...

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Publicado no:Cancer Cell
Main Authors: Li, Chia-Wei, Lim, Seung-Oe, Chung, Ezra M., Kim, Yong-Soo, Park, Andrew H., Yao, Jun, Cha, Jong-Ho, Xia, Weiya, Chan, Li-Chuan, Kim, Taewan, Chang, Shih-Shin, Lee, Heng-Huan, Chou, Chao-Kai, Liu, Yen-Liang, Yeh, Hsin-Chih, Perillo, Evan P., Dunn, Andrew K., Kuo, Chu-Wei, Khoo, Kay-Hooi, Hsu, Jennifer L., Wu, Yun, Hsu, Jung-Mao, Yamaguchi, Hirohito, Huang, Tzu-Hsuan, Sahin, Aysegul A., Hortobagyi, Gabriel N., Yoo, Stephen S., Hung, Mien-Chie
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5824730/
https://ncbi.nlm.nih.gov/pubmed/29438695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2018.01.009
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