Deubiquitination and Stabilization of PD-L1 by CSN5

Pro-inflammatory cytokines produced in the tumor microenvironment lead to eradication of anti-tumor immunity and enhanced tumor cell survival. In the current study, we identified tumor necrosis factor alpha (TNF-α) as a major factor triggering cancer cell immunosuppression against T cell surveillanc...

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Publicado no:Cancer Cell
Main Authors: Lim, Seung-Oe, Li, Chia-Wei, Xia, Weiya, Cha, Jong-Ho, Chan, Li-Chuan, Wu, Yun, Chang, Shih-Shin, Lin, Wan-Chi, Hsu, Jung-Mao, Hsu, Yi-Hsin, Kim, Taewan, Chang, Wei-Chao, Hsu, Jennifer L., Yamaguchi, Hirohito, Ding, Qingqing, Wang, Yan, Yang, Yi, Chen, Chung-Hsuan, Sahin, Aysegul A., Yu, Dihua, Hortobagyi, Gabriel N., Hung, Mien-Chie
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5171205/
https://ncbi.nlm.nih.gov/pubmed/27866850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2016.10.010
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