Unique CD44 intronic SNP is associated with tumor grade in breast cancer: a case control study and in silico analysis

BACKGROUND: CD44 encoded by a single gene is a cell surface transmembrane glycoprotein. Exon 2 is one of the important exons to bind CD44 protein to hyaluronan. Experimental evidences show that hyaluronan–CD44 interaction intensifies the proliferation, migration, and invasion of breast cancer cells....

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Bibliographic Details
Published in:Cancer Cell Int
Main Authors: Esmaeili, Rezvan, Abdoli, Nasrin, Yadegari, Fatemeh, Neishaboury, Mohamadreza, Farahmand, Leila, Kaviani, Ahmad, Majidzadeh-A, Keivan
Format: Artigo
Language:Inglês
Published: BioMed Central 2018
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Primary Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5824488/
https://ncbi.nlm.nih.gov/pubmed/29483847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-018-0522-2
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