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Purine– and pyrimidine–triple-helix-forming oligonucleotides recognize qualitatively different target sites at the ribosomal DNA locus

Triplexes are noncanonical DNA structures, which are functionally associated with regulation of gene expression through ncRNA targeting to chromatin. Based on the rules of Hoogsteen base-pairing, polypurine sequences of a duplex can potentially form triplex structures with single-stranded oligonucle...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:RNA
Asıl Yazarlar: Maldonado, Rodrigo, Filarsky, Michael, Grummt, Ingrid, Längst, Gernot
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cold Spring Harbor Laboratory Press 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5824356/
https://ncbi.nlm.nih.gov/pubmed/29222118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.063800.117
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