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Triple helix formation by purine-rich oligonucleotides targeted to the human dihydrofolate reductase promoter.

The ability of oligodeoxynucleotides to form specific triple helical structures with critical regulatory sequences in the human dihydrofolate reductase (DHFR) promoter was investigated. A battery of purine-rich oligonucleotides targeted to the two purine.pyrimidine strand biased regions near the DHF...

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Detalhes bibliográficos
Main Authors: Blume, S W, Gee, J E, Shrestha, K, Miller, D M
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC312270/
https://ncbi.nlm.nih.gov/pubmed/1579471
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