Evolutionary basis of HLA-DPB1 alleles affects acute GVHD in unrelated donor stem cell transplantation

HLA-DPB1 T-cell epitope (TCE) mismatching algorithm and rs9277534 SNP at the 3′ untranslated region (3′UTR) in the HLA-DPB1 gene are key factors for transplant-related events in unrelated hematopoietic cell transplantation (UR-HCT). However, the association of these 2 mechanisms has not been elucida...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Morishima, Satoko, Shiina, Takashi, Suzuki, Shingo, Ogawa, Seishi, Sato-Otsubo, Aiko, Kashiwase, Koichi, Azuma, Fumihiro, Yabe, Toshio, Satake, Masahiro, Kato, Shunichi, Kodera, Yoshihisa, Sasazuki, Takehiko, Morishima, Yasuo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2018
Assuntos:
Transplantation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5824334/
https://ncbi.nlm.nih.gov/pubmed/29246901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-08-801449
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