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Association of Mismatch Repair Mutation With Age at Cancer Onset in Lynch Syndrome: Implications for Stratified Surveillance Strategies
IMPORTANCE: Lynch syndrome is caused by dominantly inherited germline mutations that predispose individuals to colorectal, endometrial, ovarian, and other cancers through inactivation of the cellular mismatch repair system. Lynch syndrome–associated cancers are amenable to surveillance strategies th...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | JAMA Oncol |
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| Κύριοι συγγραφείς: | , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American Medical Association
2017
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5824283/ https://ncbi.nlm.nih.gov/pubmed/28772289 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2017.0619 |
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