Associations of Luminal and Basal Subtyping of Prostate Cancer With Prognosis and Response to Androgen Deprivation Therapy

IMPORTANCE: There is a clear need for a molecular subtyping approach in prostate cancer to identify clinically distinct subgroups that benefit from specific therapies. OBJECTIVES: To identify prostate cancer subtypes based on luminal and basal lineage and to determine associations with clinical outc...

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Dettagli Bibliografici
Pubblicato in:JAMA Oncol
Autori principali: Zhao, Shuang G., Chang, S. Laura, Erho, Nicholas, Yu, Menggang, Lehrer, Jonathan, Alshalalfa, Mohammed, Speers, Corey, Cooperberg, Matthew R., Kim, Won, Ryan, Charles J., Den, Robert B., Freedland, Stephen J., Posadas, Edwin, Sandler, Howard, Klein, Eric A., Black, Peter, Seiler, Roland, Tomlins, Scott A., Chinnaiyan, Arul M., Jenkins, Robert B., Davicioni, Elai, Ross, Ashley E., Schaeffer, Edward M., Nguyen, Paul L., Carroll, Peter R., Karnes, R. Jeffrey, Spratt, Daniel E., Feng, Felix Y.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Medical Association 2017
Soggetti:
Original Investigation
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5824281/
https://ncbi.nlm.nih.gov/pubmed/28494073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2017.0751
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