Associations of Luminal and Basal Subtyping of Prostate Cancer With Prognosis and Response to Androgen Deprivation Therapy

IMPORTANCE: There is a clear need for a molecular subtyping approach in prostate cancer to identify clinically distinct subgroups that benefit from specific therapies. OBJECTIVES: To identify prostate cancer subtypes based on luminal and basal lineage and to determine associations with clinical outc...

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Detalhes bibliográficos
Publicado no:JAMA Oncol
Main Authors: Zhao, Shuang G., Chang, S. Laura, Erho, Nicholas, Yu, Menggang, Lehrer, Jonathan, Alshalalfa, Mohammed, Speers, Corey, Cooperberg, Matthew R., Kim, Won, Ryan, Charles J., Den, Robert B., Freedland, Stephen J., Posadas, Edwin, Sandler, Howard, Klein, Eric A., Black, Peter, Seiler, Roland, Tomlins, Scott A., Chinnaiyan, Arul M., Jenkins, Robert B., Davicioni, Elai, Ross, Ashley E., Schaeffer, Edward M., Nguyen, Paul L., Carroll, Peter R., Karnes, R. Jeffrey, Spratt, Daniel E., Feng, Felix Y.
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2017
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5824281/
https://ncbi.nlm.nih.gov/pubmed/28494073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2017.0751
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