Associations of Luminal and Basal Subtyping of Prostate Cancer With Prognosis and Response to Androgen Deprivation Therapy

IMPORTANCE: There is a clear need for a molecular subtyping approach in prostate cancer to identify clinically distinct subgroups that benefit from specific therapies. OBJECTIVES: To identify prostate cancer subtypes based on luminal and basal lineage and to determine associations with clinical outc...

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Опубликовано в: :JAMA Oncol
Главные авторы: Zhao, Shuang G., Chang, S. Laura, Erho, Nicholas, Yu, Menggang, Lehrer, Jonathan, Alshalalfa, Mohammed, Speers, Corey, Cooperberg, Matthew R., Kim, Won, Ryan, Charles J., Den, Robert B., Freedland, Stephen J., Posadas, Edwin, Sandler, Howard, Klein, Eric A., Black, Peter, Seiler, Roland, Tomlins, Scott A., Chinnaiyan, Arul M., Jenkins, Robert B., Davicioni, Elai, Ross, Ashley E., Schaeffer, Edward M., Nguyen, Paul L., Carroll, Peter R., Karnes, R. Jeffrey, Spratt, Daniel E., Feng, Felix Y.
Формат: Artigo
Язык:Inglês
Опубликовано: American Medical Association 2017
Предметы:
Original Investigation
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5824281/
https://ncbi.nlm.nih.gov/pubmed/28494073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2017.0751
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