Humane Endpoints for Guinea Pigs Used for Mycobacterium tuberculosis Vaccine Research

Guinea pigs are a commonly used model for tuberculosis vaccine research. Loss of body weight is the most frequently described humane endpoint for animals used in these studies. During a chronic study, we noted labored breathing in some tuberculosis-infected guinea pigs. To develop consistent humane...

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Detalhes bibliográficos
Publicado no:Comp Med
Main Authors: Collymore, Chereen, Kent, Laura, Ahn, Sang Kyun, Xu, Wenxi, Li, Ming, Liu, Jun, Turner, Patricia V, Banks, E Kate
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for Laboratory Animal Science 2018
Assuntos:
Guinea Pig Model
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5824138/
https://ncbi.nlm.nih.gov/pubmed/29460720
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