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Leveraging Population‐Based Clinical Quantitative Phenotyping for Drug Repositioning

Computational drug repositioning methods can scalably nominate approved drugs for new diseases, with reduced risk of unforeseen side effects. The majority of methods eschew individual‐level phenotypes despite the promise of biomarker‐driven repositioning. In this study, we propose a framework for di...

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Detaylı Bibliyografya
Yayımlandı:CPT Pharmacometrics Syst Pharmacol
Asıl Yazarlar: Brown, Adam S., Rasooly, Danielle, Patel, Chirag J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5824113/
https://ncbi.nlm.nih.gov/pubmed/28941007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psp4.12258
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