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The Role of Hippo Pathway in Cancer Stem Cell Biology

The biological significance and deregulation of the Hippo pathway during organ growth and tumorigenesis have received a surge of interest in the past decade. The Hippo pathway core kinases, MST1/2 and LATS1/2, are tumor suppressors that inhibit the oncogenic nuclear function of YAP/TAZ and TEAD. In...

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Détails bibliographiques
Publié dans:Mol Cells
Auteurs principaux: Park, Jae Hyung, Shin, Ji Eun, Park, Hyun Woo
Format: Artigo
Langue:Inglês
Publié: Korean Society for Molecular and Cellular Biology 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5824027/
https://ncbi.nlm.nih.gov/pubmed/29429151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14348/molcells.2018.2242
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