IL-35 Suppresses Endothelial Cell Activation by Inhibiting Mitochondrial ROS-mediated Site-specific Acetylation of Histone 3 Lysine 14

OBJECTIVE: IL-35 is an anti-inflammatory cytokine, which inhibits immune responses by inducing regulatory T cells and regulatory B cells, and suppressing effector T cells and macrophages. It remains unknown whether atherogenic stimuli induce IL-35, and whether IL-35 inhibits atherogenic lipid-induce...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Li, Xinyuan, Shao, Ying, Sha, Xiaojin, Fang, Pu, Kuo, Yin-Ming, Andrews, Andrew J., Li, Yafeng, Yang, William Y., Maddaloni, Massimo, Pascual, David W., Luo, Jin J., Jiang, Xiaohua, Wang, Hong, Yang, Xiaofeng
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5823772/
https://ncbi.nlm.nih.gov/pubmed/29371247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.117.310626
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