Interleukin-35 Inhibits Endothelial Cell Activation by Suppressing MAPK-AP-1 Pathway

Vascular response is an essential pathological mechanism underlying various inflammatory diseases. This study determines whether IL-35, a novel responsive anti-inflammatory cytokine, inhibits vascular response in acute inflammation. Using a mouse model of LPS-induced acute inflammation and plasma sa...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Sha, Xiaojin, Meng, Shu, Li, Xinyuan, Xi, Hang, Maddaloni, Massimo, Pascual, David W., Shan, Huimin, Jiang, Xiaohua, Wang, Hong, Yang, Xiao-feng
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4521049/
https://ncbi.nlm.nih.gov/pubmed/26085094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.663286
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