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Prenatal Kynurenine Treatment in Rats Causes Schizophrenia-like Broad Monitoring Deficits in Adulthood
RATIONALE: Elevated brain kynurenic acid (KYNA) levels are implicated in the pathology and neurodevelopmental pathogenesis of schizophrenia. In rats, embryonic treatment with kynurenine (EKyn) causes elevated brain KYNA levels in adulthood, and cognitive deficits reminiscent of schizophrenia. OBJECT...
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Publicado no: | Psychopharmacology (Berl) |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5823752/ https://ncbi.nlm.nih.gov/pubmed/29128872 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-017-4780-9 |
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