MLK3 phosphorylation by ERK1/2 is required for oxidative stress-induced invasion of colorectal cancer cells

Mixed lineage kinase 3 (MLK3) functions in migration and/or invasion of several human cancers; however, the role of MLK3 in colorectal cancer (CRC) invasion is unknown. MLK3 is a mitogen-activated protein kinase (MAPK) kinase kinase (MAP3K) which activates MAPK pathways through either kinase-depende...

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Gepubliceerd in:Oncogene
Hoofdauteurs: Schroyer, April L., Stimes, Nicholas W., Abi Saab, Widian F., Chadee, Deborah N.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5823719/
https://ncbi.nlm.nih.gov/pubmed/29084209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2017.396
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