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Mixed Lineage Kinase 3 is Required for Matrix Metalloproteinase Expression and Invasion in Ovarian Cancer Cells

Mixed lineage kinase 3 (MLK3) is a mitogen-activated protein kinase kinase kinase (MAP3K) that activates MAPK signaling pathways and regulates cellular responses such as proliferation, migration and apoptosis. Here we report high levels of total and phospho-MLK3 in ovarian cancer cell lines in compa...

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Detalhes bibliográficos
Main Authors: Zhan, Yu, Abi Saab, Widian F., Modi, Nidhi, Stewart, Amanda M., Liu, Jinsong, Chadee, Deborah N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3389280/
https://ncbi.nlm.nih.gov/pubmed/22652451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2012.05.002
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