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De novo variants in the alternative exon 5 of SCN8A cause epileptic encephalopathy

PURPOSE: As part of the Epilepsy Genetics Initiative, we re-evaluated clinically generated exome sequence data from 54 epilepsy patients and their unaffected parents to identify molecular diagnoses not provided in the initial diagnostic interpretation. METHODS: We compiled and analyzed exome sequenc...

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Bibliografske podrobnosti
izdano v:Genet Med
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5823708/
https://ncbi.nlm.nih.gov/pubmed/29121005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gim.2017.100
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