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Development of novel miR-129 mimics with enhanced efficacy to eliminate chemoresistant colon cancer stem cells
BACKGROUND: Resistance to 5-Fluorouracil (5-FU) based chemotherapy is the major reason for failure of treating patients with advanced colorectal cancer. MATERIALS AND METHODS: In this study, we developed a novel miR-129 mimic with potent efficacy in eliminating resistant colon cancer stem cells both...
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| Publié dans: | Oncotarget |
|---|---|
| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Impact Journals LLC
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5823633/ https://ncbi.nlm.nih.gov/pubmed/29507661 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22322 |
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