Mechanism of chemoresistance mediated by miR-140 in human osteosarcoma and colon cancer cells

In this study, our high throughput microRNA (miRNA) expression analysis revealed that the expression of miR-140 was associated with chemosensitivity in osteosarcoma tumor xenografts. Tumor cells ectopically transfected with miR-140 were more resistant to methotrexate (MTX) and 5-fluorouracil (5-FU)....

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Main Authors: Song, Bo, Wang, Yuan, Xi, Yaguang, Kudo, Kenji, Bruheim, Skjalg, Botchkina, Galina I., Gavin, Elaine, Wan, Yu, Formentini, Andrea, Kornmann, Marko, Fodstad, Oystein, Ju, Jingfang
Format: Artigo
Jezik:Inglês
Izdano: 2009
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783211/
https://ncbi.nlm.nih.gov/pubmed/19734943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.274
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