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miR-192 Regulates Dihydrofolate Reductase and Cellular Proliferation Through the p53-miRNA Circuit

PURPOSE: The purpose of this study is to investigate the molecular mechanism of miR-192 in colon cancer. EXPERIMENTAL DESIGN: Human colon cancer cell lines with different p53 status were used as our model system to study the impact of miR-192 on cell proliferation, cell cycle control and mechanism o...

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Detalhes bibliográficos
Main Authors: Song, Bo, Wang, Yuan, Kudo, Kenji, Gavin, Elaine J., Xi, Yaguang, Ju, Jingfang
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2653201/
https://ncbi.nlm.nih.gov/pubmed/19088023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-1422
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