Preclinical evaluation of the PI3K/Akt/mTOR pathway in animal models of multiple sclerosis

The PI3K/AKT/mTOR pathway is an intracellular signalling pathway that regulates cell activation. proliferation, metabolism and apoptosis. Increasing body of data suggests that alterations in the PI3K/AKT/mTOR pathway may result in an enhanced susceptibility to autoimmunity. Multiple Sclerosis (MS) i...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Mammana, Santa, Bramanti, Placido, Mazzon, Emanuela, Cavalli, Eugenio, Basile, Maria Sofia, Fagone, Paolo, Petralia, Maria Cristina, McCubrey, James Andrew, Nicoletti, Ferdinando, Mangano, Katia
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Research Paper: Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5823598/
https://ncbi.nlm.nih.gov/pubmed/29492193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23862
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