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Reproducibility of preclinical animal research improves with heterogeneity of study samples

Single-laboratory studies conducted under highly standardized conditions are the gold standard in preclinical animal research. Using simulations based on 440 preclinical studies across 13 different interventions in animal models of stroke, myocardial infarction, and breast cancer, we compared the ac...

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Detalhes bibliográficos
Publicado no:PLoS Biol
Main Authors: Voelkl, Bernhard, Vogt, Lucile, Sena, Emily S., Würbel, Hanno
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5823461/
https://ncbi.nlm.nih.gov/pubmed/29470495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2003693
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