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Reproducibility of preclinical animal research improves with heterogeneity of study samples

Single-laboratory studies conducted under highly standardized conditions are the gold standard in preclinical animal research. Using simulations based on 440 preclinical studies across 13 different interventions in animal models of stroke, myocardial infarction, and breast cancer, we compared the ac...

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Dades bibliogràfiques
Publicat a:PLoS Biol
Autors principals: Voelkl, Bernhard, Vogt, Lucile, Sena, Emily S., Würbel, Hanno
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5823461/
https://ncbi.nlm.nih.gov/pubmed/29470495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2003693
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