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Genetic Etiologies for Phenotypic Diversity in Sickle Cell Anemia

The clinical course of patients with sickle cell anemia, a Mendelian trait, is characteristically highly variable. HbF concentration and the presence of a thalassemia are established modulators of the disease, but cannot account for all of its clinical heterogeneity. To find additional genetic modul...

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Bibliografske podrobnosti
izdano v:ScientificWorldJournal
Glavni avtor: Steinberg, Martin H.
Format: Artigo
Jezik:Inglês
Izdano: TheScientificWorldJOURNAL 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5823205/
https://ncbi.nlm.nih.gov/pubmed/19151898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1100/tsw.2009.10
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