Successful treatment of post-transplant relapsed acute myeloid leukemia with FLT3 internal tandem duplication using the combination of induction chemotherapy, donor lymphocyte infusion, sorafenib and azacitidine. Report of three cases

Acute myeloid leukemia is a hematopoietic stem cell neoplastic disease associated with high morbidity and mortality. The presence of FLT3 internal tandem duplication mutations leads to high rates of relapse and decreased overall survival. Patients with FLT3 internal tandem duplication are normally t...

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Vydáno v:Einstein (Sao Paulo)
Hlavní autoři: Campregher, Paulo Vidal, de Mattos, Vinicius Renan Pinto, Salvino, Marco Aurélio, Santos, Fabio Pires de Souza, Hamerschlak, Nelson
Médium: Artigo
Jazyk:Inglês
Vydáno: Instituto Israelita de Ensino e Pesquisa Albert Einstein 2017
Témata:
Case Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5823052/
https://ncbi.nlm.nih.gov/pubmed/28746590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/S1679-45082017RC3784
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