Phase 2 study of azacytidine plus sorafenib in patients with acute myeloid leukemia and FLT-3 internal tandem duplication mutation

Patients received 5-azacytidine (AZA) 75 mg/m(2) intravenously daily for 7 days and sorafenib 400 mg orally twice daily continuously; cycles were repeated at ∼1-month intervals. Forty-three acute myeloid leukemia (AML) patients with a median age of 64 years (range, 24-87 years) were enrolled; 37 wer...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Ravandi, Farhad, Alattar, Mona Lisa, Grunwald, Michael R., Rudek, Michelle A., Rajkhowa, Trivikram, Richie, Mary Ann, Pierce, Sherry, Daver, Naval, Garcia-Manero, Guillermo, Faderl, Stefan, Nazha, Aziz, Konopleva, Marina, Borthakur, Gautam, Burger, Jan, Kadia, Tapan, Dellasala, Sara, Andreeff, Michael, Cortes, Jorge, Kantarjian, Hagop, Levis, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2013
Assuntos:
Clinical Trials and Observations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674666/
https://ncbi.nlm.nih.gov/pubmed/23613521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-01-480228
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados