Autophagy Stimulus Promotes Early HuR Protein Activation and p62/SQSTM1 Protein Synthesis in ARPE-19 Cells by Triggering Erk1/2, p38(MAPK), and JNK Kinase Pathways

RNA-binding protein dysregulation and altered expression of proteins involved in the autophagy/proteasome pathway play a role in many neurodegenerative disease onset/progression, including age-related macular degeneration (AMD). HuR/ELAVL1 is a master regulator of gene expression in human physiopath...

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Publicado en:Oxid Med Cell Longev
Autores principales: Marchesi, Nicoletta, Thongon, Natthakan, Pascale, Alessia, Provenzani, Alessandro, Koskela, Ali, Korhonen, Eveliina, Smedowski, Adrian, Govoni, Stefano, Kauppinen, Anu, Kaarniranta, Kai, Amadio, Marialaura
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5822911/
https://ncbi.nlm.nih.gov/pubmed/29576851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/4956080
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