Autophagy Activation Clears ELAVL1/HuR-Mediated Accumulation of SQSTM1/p62 during Proteasomal Inhibition in Human Retinal Pigment Epithelial Cells

Age-related macular degeneration (AMD) is the most common reason of visual impairment in the elderly in the Western countries. The degeneration of retinal pigment epithelial cells (RPE) causes secondarily adverse effects on neural retina leading to visual loss. The aging characteristics of the RPE i...

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Main Authors: Viiri, Johanna, Amadio, Marialaura, Marchesi, Nicoletta, Hyttinen, Juha M. T., Kivinen, Niko, Sironen, Reijo, Rilla, Kirsi, Akhtar, Saeed, Provenzani, Alessandro, D'Agostino, Vito Giuseppe, Govoni, Stefano, Pascale, Alessia, Agostini, Hansjurgen, Petrovski, Goran, Salminen, Antero, Kaarniranta, Kai
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3726683/
https://ncbi.nlm.nih.gov/pubmed/23922739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069563
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